Combination Therapy of AIDS

Birkhäuser, 2003. 240 p., Gebunden

ISBN: 978-3-7643-6600-1

234,33 €

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Mitarbeiter: Ed. by E. De Clerq and A. Vandamme

This book is the first to tackle, in a single treatise, a subject that has recently become a discipline in its own right, that of the combination antiretroviral therapy of AIDS. It is aimed at an audience of clinicians, researchers, public health workers, specialists or non-specialists in AIDS and particularly those who want to know how to optimally approach the treatment of AIDS. Combination drug treatment of AIDS is focussed from different angles and perspectives, historical,basic, economic, theoretical, virological, immunological, clinical and practical reasons for therapy failures are examined and strategies to prevent or overcome failing therapies are formulated. This book fills a gap in the current literature on clinical therapeutics. It should be particularly informative to those who want and need to know more about the current treatment of AIDS, with its successes and failures, but also with lessons and guidelines to affront these failures.

Anti-HIV agents to be used in combination drug regimens.- A perspective of the history of HAART.- The basic principles for combination therapy.- Comparison of the efficacy of HAART: single, dual or triple-class antiretroviral therapy.- Primary HIV infection: From diagnosis to treatment.- Salvage therapy.- Structured therapy interruptions (STIs): Lessons from a therapeutic strategy.- Immune reconstitution in HIV infection.- Highly active antiretroviral treatment (HAART) of pediatric HIV-1 infection.- Causes of HIV treatment failure.- Economic implication of HIV-1 resistance testing in overall clinical care.- Guidelines for antiretroviral therapy



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